Page 4: Making Layouts using GoLive's Grid Object

[Home] [Page 1] [Page 2] [Page 3] [Page 4] [Page 5] [Page 6] [Page 7]


Using Grids To Lay Out Objects

Structure of 3-isopropylmalate dehydrogenase in complex with 3-isopropylmalate at 2.0 A resolution: the role of Glu88 in the unique substrate-recognition mechanism.

Imada K, Inagaki K, Matsunami H, Kawaguchi H, Tanaka H, Tanaka N, Namba K.

International Institute for Advanced Research, Matsushita Electric Industrial Co., Ltd., Seika, Japan. kimada@npn.jst.go.jp

BACKGROUND: 3-Isopropylmalate dehydrogenase (IPMDH) and isocitrate dehydrogenase (ICDH) belong to a unique family of bifunctional decarboxylatingsdehydrogenases. Although the ICDH dimer catalyzes its reaction under a closed conformation, known structures of the IPMDH dimer (without substrate) adopt as fully open or a partially closed form. Considering the similarity in the catalytic mechanism, the IPMDH dimer must be in a fully closed conformation during this reaction. A large conformational change should therefore occur upon substrate binding.


      1. Drag the Layout Grid button from the Object palette to the web page:

      2. This will place a grid on the page:
      3. The grid can be resized to whatever size is desired.
      4. Image and plugin ojects can be placed on the grid and linked to source files as described on pages 2 and 3 .
      5. Text is placed on the layout grid by dragging the Layout Text Box object from the Object palette onto the layout grid, resizing the box and entering text into it:

[Home] [Page 1] [Page 2] [Page 3] [Page 4] [Page 5] [Page 6] [Page 7]