Page 3: Using Tables to Display
Embedded Chimes and Buttons

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Tables

Structure of 3-isopropylmalate dehydrogenase in complex with 3-isopropylmalate at 2.0 A resolution: the role of Glu88 in the unique substrate-recognition mechanism.

Imada K, Inagaki K, Matsunami H, Kawaguchi H, Tanaka H, Tanaka N, Namba K.

International Institute for Advanced Research, Matsushita Electric Industrial Co., Ltd., Seika, Japan. kimada@npn.jst.go.jp

BACKGROUND: 3-Isopropylmalate dehydrogenase (IPMDH) and isocitrate dehydrogenase (ICDH) belong to a unique family of bifunctional decarboxylatingsdehydrogenases. Although the ICDH dimer catalyzes its reaction under a closed conformation, known structures of the IPMDH dimer (without substrate) adopt as fully open or a partially closed form. Considering the similarity in the catalytic mechanism, the IPMDH dimer must be in a fully closed conformation during this reaction. A large conformational change should therefore occur upon substrate binding.

      1. Drag the Table button from the Object palette:


      2. This will place a 3 x 3 table on the page.

      3. To select a cell within the table, click on the bottom border of a cell. To select the entire table, click on the upper border of the table. The Inspector palette will change depending on what is selected. The Inspector palette can be used to set the number of rows and columns in the table. It can also be used the set the width of the borders and the padding between the borders and the cell contents.

      4. If the border is set to 0, then the table grid will not be seen:

Buttons

      1. Drag the Plugin button from the Object palette and place it on the web page.
      2. Select the plugin placeholder and in the Inspector palette, Basic tab, uncheck the File checkbox and check the "Mime" checkbox:

      3. In the Mime textbox type in "application/x-spt". This indicates to the browser that the button will be used to send a script to a Chime plugin. An appropriate width and height for the button should also be indicated; 12 x 12 or 16 x 16 work best.
      4. There is nothing that needs to be filled in on the "More" tab; buttons do not need to be named.
      5. On the Attrib tab, three attributes must be stipulated for Chime buttons:
        button = "push"( or "toggle")
        target = "        Chime plugin name"
        script = "Rasmol commands"

      6. Once you have successfully created a button it can be copied and pasted and the values for target and script attributes changed to create additional buttons.

      This Chime image was created by copying and pasting it from above. Its name was changed from "modelC" to "modelB" so that the images can be individually targeted with buttons.
      This push button turns on a spacefill model for the substrate and colors it according to atom type (cpk). It also resets the orietation of the model to that used on Page 2. It changes the protein representation to strands and colors it white.

      This toggle button turns on and off the spinning.

      1. Enter the value "toggle" for the button attribute.
      2. Include the alscript attribute

Resource for Button Scripts

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