Though these may seem similar in a larger sense, they are also very different. They all belong to the same class of enzymes and react similarly as described above, but they also vary in a number of ways. First is the bonds each breaks. The amylase breaks glycosidic bonds, penicillin acylase breaks amide linkages, and pyrophosphatase breaks phosphate bonds. All three of the enzymes also have specific pH conditions that must be met. Each is involved in different cellular processes and are located in different parts of the cell. Besides cellular location, some enzymes such as amylase are only produce by certain organs. All these differences only brush over the vast amounts of subtle yet significant requirements of each enzyme that gives them each specific characteristics. By simply looking at the class of an enzyme, you are only getting a narrow view of the wide possibilities of that enzyme.
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Rydberg, Edwin H. Cloning, mutagenesis, and structural analysis of human pancreatic alpha-amylase expressed in Pichia pastoris. Protein Science, vol. 8, pp. 635-643, 1999.
Stryer, Lubert. Biochemistry [fifth ed.]. W.H. Freeman and Company, New York. 2002.
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