Home | Introduction | DNA Binding | DNA Separation | DNA Unwinding | Conclusion | References Ali, Janid A., et al. (1997). Kinetic Measurement of the Step Size of DNA Unwinding by Escherichia coli UVRD Helicase. Science, 275(5298), Jan. 17, 377-81. Biswas, Esther E., et al. (1999). Mechanism of DnaB Helicase of Escherichia coli: Structural Domains Involved in ATP Hydrolysis, DNA Binding, and Oligomerization. Biochemistry, 38(34), Aug. 24, 10919-28. Bujalowski, Wlodzimierz, et al. (2000). Kinetic Mechanism of Nucleotide Cofactor Binding to Escherichia coli Replicative Helicase DnaB Protein. Stopped-Flow Kinetic Studies Using Fluorescent, Ribose-, and Base-Modified Nucleotide Analogues. Biochemistry, 39(8), Feb. 29, 2106-22. Dillingham, Mark S., et al. (2002). Direct Measurement of Single-Stranded DNA Translocation by PcrA Helicase Using the Fluorescent Base Analogue 2-Aminopurine. Biochemistry, 41(2), Jan. 15, 643-51. Duguet, M., (1997). When Helicase and Topoisomerase Meet! J. Cell Sci. 110(12), June, 1345-1350. Kim, D.E., (2002). T7 DNA Helicase: A Molecular Motor That Processively and Unidirectionally Translocates Along Single-Stranded DNA. J. Mol. Biol., 321(5), Aug. 30, 807-19. Matsumoto, K., et al. (1995). Stimulation of DNA-Synthesis by Mouse DNA Helicase-B in a DNA-Replication System Containing Eukaryotic Replication Origins. Biochemistry, 34(24), June 20, 7913-7922. Picha, K.M., et al. (2000). DNA Binding in the Central Channel of Bacteriophage T7 Helicase-Primase is a Multistep Process. Nucleotide Hydrolysis Is Not Required. Biochemistry, 39(21), May 30, 6401-09. Sawaya, Michael R., et al. (1999). Crystal Structure of the Helicase Domain from the Replicative Helicase-Primase of Bacteriophage T7. Cell, 99, Oct. 15, 167-177. Tackett, Alan J., et al. (2001). Unwinding of Unnatural Substrates by a DNA Helicase. Biochemistry, 40(2), Jan. 16, 543-48. Xu, Hai, et al. (2001). Interaction of Fluorescence Labeled Single-Stranded DNA with Hexameric DNA-Helicase RepA: A Photon and Fluorescence Correlation Spectroscopy Study. Biochemistry, 40(24), June 19, 7211-18. ADDITIONAL RESOURCES: If you would like to find out more about the protein complexes used as visual aids in this site, follow the links below to their Protein Data Bank files. 1A31-Topoisomerase I complexed with dsDNA 1CR2-Gp4D Helicase from bacteriophage T7 bound to dATP 1E0K-Gp4D Helicase 1UAA-Rep Helicase from E. coli complexed with ssDNA 3PJR-PcrA Helicase from Bacillus stearothermophilus bound to dsDNA
ADDITIONAL RESOURCES:
If you would like to find out more about the protein complexes used as visual aids in this site, follow the links below to their Protein Data Bank files.
1A31-Topoisomerase I complexed with dsDNA
1CR2-Gp4D Helicase from bacteriophage T7 bound to dATP
1E0K-Gp4D Helicase
1UAA-Rep Helicase from E. coli complexed with ssDNA
3PJR-PcrA Helicase from Bacillus stearothermophilus bound to dsDNA
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