Aldehyde reductase is a cytoplasmic protein that is a member of the aldo-keto reductase superfamily, a category of enzymes that are responsible for a wide array of biological functions. “These include the regulation of the proinflammatory response via the reduction of aldehyde phospholipids, the synthesis of metabolically vital compounds such as prostaglandins, and the modulation and modification of steroids in vivo, which include progesterone signaling in breast mammary cells”
(2.) Aldehyde reductase has high sequential (approximately 65%) and structural homology with another member of this class, aldose reductase, both of which “catalyze the NADPH-dependent reduction of aldehydes, xenobiotic aldehydes, ketones, trioses, and triose phosphates" although aldehyde reductase prefers aromatic aldehydes
(2.)