Readings
Lecture 1- Introduction
- Science Editorial: Carl Zimmer, "On the Origin of Life on Earth", Science 2009, 330, 198-199.
- Biller, S. J., Schubotz, F., Roggensack, S. E., Thompson, A. W., Summons, R. E., and Chisholm, S. W. "Bacterial Vesicles in Marine Ecosystems." Science 2014, 343, 183–186.
- Drawing of and E.coli cell: David S. Goodsell, "Escherichia coli", Biochemistry and Molecular Biology Education 2009, 37, 325-329.
- Science Editorial: "Body's Hardworking Microbes Get Some Overdue Respect", Science 2010, 323, 1691.
Lecture 3 - Proteins
- Perspectives on Genetics: Antony Stretton, "The First Sequence: Fred Sanger and Insulin", Genetics 2002, 162, 527-532.
Lecture 4 - Enzymes
- Michaelis, L. & Menton M.L., "Die Kinetik der Invertinwirkung" Biochemische Zeitschrift. 1913, 49,333–369.
Lecture 11 - Nucleic Acids
- Pauling, L. & Corey, R., "A Proposed Structure for the Nucleic Acids" Proceedings of the National Academy of Science 1953 39, 84-97.
- Wilkins et al., Nature 1953 171, 738-740.
- Franklin & Gosling, Nature 1953 171, 740-741.
- Watson, J. and Crick, F., Nature 1953 171, 737-738.
Lecture 13 - Transcription and RNA Processing
- Murakami et al. Science 2002 296, 1285-1290
Lecture 14 - Protein Synthesis
- Press Release for 2009 Nobel Prize in Chemistry
- Schmeing, T. M. & Ramakrishnan, V. "What recent ribosome structures have revealed about the mechanism of translation." Nature 2009 461, 1234-1242.
- Towards understanding the mechanism of multi-drug resistance in bacteria. Grove, T. L., Benner, J. S., Radle, M. I., Ahlum, J. H., Landgraf, B. J., Krebs, C., and Booker, S. J. (2011) A radically different mechanism for S-adenosylmethionine-dependent methyltransferases, Science 2011 332, 604-607.