Chemistry/Biology 491"Molecules and Medicine"

1. Topic 1 Organic Structures and Interactions of Drugs
   
2. Topic 2 Proteins as Drug Targets-Protein Structure
   
3. Topic 3 Proteins as Drug Targets-Enzymes
1. PDB Supplement-SrcTyrosineKinase
   
4. Topic 4 Proteins as Drug Targets-Receptors
1. Supplement-Ligand Binding and Dose/Response
2. PDB Supplement-Adrenergic receptors
3. PDB Supplement-Estrogen receptors
5. Topic 5 Nucleic Acids as Drug Targets
1. PDB Supplement-Small Interfering RNAs
6.  Topic 6-Pharmacokinetics and Drug Metabolism
1. PDB Supplement- Cytochrome P450
7. Topic 7.1-Drug Discovery and Design Pt. 1
8. Topic 7.2-Drug Discovery and Design Pt. 2
   
9. Topic 8.1- Antibacterial Agents-beta-Lactams
10. Topic 8.2-Other Antiinfectives
    
11. Topic 9.1-Intro- Antineoplastic Agents
12. Topic 10.1-Agents Acting on the nervous system-Cholinergic
13. Topic 10.2-Agents Acting on the nervous system-Adrenergic
14. Topic 11- Coronary Artery Disease
15. Topic 12- Protein Folding Diseases
16. Topic 13- Diabetes

1. Placebo Effect
2. Patrick Problems #1
3. Quiz 1 Key
4. Patrick Problems #2
5. Study Problems for Review. 8-3,5,6; 10-3,8,9; 11- 4,7-KEY
6. Review Questions on Basic Pharmacology
7. Exam 1 Key