This web page requires Chime to view the topoisomerase I molecules. Each section contains buttons which affect the molecule when pushed. Please push all buttons in order, otherwise the result on the molecule may be unexpected. Some buttons are slower than others - please be patient.
Description of the biological significance of topoisomerase I
and the reaction it catalyzes
Description of the biological source and cellular location of
topoisomerase I
Description of the reaction catalyzed by topoisomerase I
Description of the tertiary structure of topoisomerase I
Description of the active site and catalytic strategy of topoisomerase
I
Description of control mechanisms
Updated: December 6, 1998
Designed for Chem 406 - Biophysical Chemistry by Anne C. Luebke
Comments, Questions: luebkeac@uwec.edu