Overview of Transcription

Comparison of Prokaryotic and Eukaryotic Transcription

Eukaryotic Transcription details

Effects of Amanitin

Stem Cell Research

Artificial Transcription Factors

References

(1) Armache, K.J., Kettenberger, H., and Cramer, P.  Architecture of Initiation- competent 12-subunit RNA Polymerase II.  PNAS. 2003. 100 6964-6968.

 

(2) Armache, K.J., Mitterweger, A.M., and Cramer, P. Structures of Complete RNA             Polymerase II and Its Subcomplex Rpb4/7.  Biological Chemistry. 25 February 2005. 280:8 7131-7134.

(3) Bushnell, D.A., Cramer, P., Kornberg, R.D. Structural basis of transcription: alpha Amanitin-  RNA polymerase II cocrystal at 2.8 Å resolution. PNAS. 5 February 2002. 99, 1218-1222.

 

(4) Beltran, A., et al. Re-activation of a dormant tumor suppressor gene maspin by             designed transcription factors.  Oncogene. 23 October 2006.

 

(5) Cramer, et al. Architecture of RNA Polymerase II and the Implications for the             Transcription Mechanism.  Science. 28 April 2000. 288, 640-649.

 

(6) Cramer, P., Bushnell, D.A., Kornberg, R.D. Structural Basis of Transcription: RNA             Polymerase II at 2.8 Ångstrom Resolution. Science. 8 June 2001. 292, 1863-1876.

(7) Gnatt, A.L, Cramer, P., Fu, J., Bushnell, D.A., Kornberg, R.D. Structural Basis of             Transcription: An RNA Polymerase II Elongation Complex at 3.3 Å Resolution.             Science. 8 June 2001. 292, 1876-1882.

 

(8) Gromak, N., West, S., Proudfoot, N.J. Pause Sites Promote Transcriptional             Termination of Mammalian RNA Polymerase II. Molecular and Cellular Biology. May 2006. 26, 3986-1996.

(9) Kornberg, R.D. Nobel Lecture: “The Molecular Basis of Eukaryotic Transcription"             Nobel Lecture. December 8, 2006, at Aula Magna, Stockholm University.

 

(10) Lum, J.K., Majmudar, C.Y. Converting Inactive Peptides into Potent Transcriptional  Activators. ACS chemical biology. November 2006. 1:10 639-643.

 

(11) Minakhin, L., Bhagat, S., Brunning, A. Bacterial RNA polymerase subunit omega             and eukaryotic RNA polymerase subunit RPB6 are sequence, structural, and functional homologs and promote RNA polymerase assembly. PNAS. 30 January 2001. 98:3 892-897.

 

(12) Murakami, K.S.; Masuda, S.; Darst, S.A. Structural Basis of Transcription Initiation: RNA Polymerase Holoenzyme a 4 Å Resolution. Science. 17 May 2002. 296, 1280-1284.

 

(13) Seshadri, V., McArthur, A.G., Sogin, M.L., Adam, R.D. Giardia Lamblia RNA             polymerase II: amanitin resistant transcription. Biol Chem. 25 July 2003. 278:30, 27804-27810.

 

(14) Westover, K.D., Bushnell, D.A., Kornberg, R.D. Structural Basis of Transcription             Nucleotide Selection by Rotation in the RNA Polymerase II Active Center. Cell.  12 November 2004. 119, 481-489.

 

(15) Boyer, L.A., Lee, T.I., Cole, M.F., Johnstone, S.E., Levine, S.S., Zucker, J.P.,             Guenther, M.G., Kumar, R.M., Murray, H.L., Jenner, R.G., Gifford, D.K., Melton,             D.A., Jaenisch, R., Young, R.A. Core Transcriptional Regulatory Circuitry in Human Embryonic Stem Cells. Cell. 23 September, 2005. 122, 947-956.

 

(16) Zhang, W., Walker, E., Tramplin, O.J., Rossant, J., Stanford, W.L., Hughes, T.R.             Zfp206 regulates ES cell gene expression and differentiation. Nucleic Acids Research. 13 September 2006. 34, 4780-4790.

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