References

Structures from the Protein Data Bank: 1HCQ and 1A52

J. R. W. Schwabe L. Chapman J. T. Finch, and D. Rhodes. The Crystal Structure of the Estrogen Receptor DNA-Binding Domain Bound to DNA: How Receptors Discriminate between Their Response Elements. Cell 75 567-578, 1993.

D. M. Tenanbaum Y. Wang S. P. Williams, and P. B. Sigler. Estrogen Receptor Alpha Ligand-Binding Domain Complexed to Estradiol. Proc Natl Acad Sci USA 95 5998, 1998. View this article on the web.

Picture of estrogen taken from http://opbs.okstate.edu/~kelley/Chapter12/Chapter12.htm

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ER binding to the ERE

Zinc-binding Motif

Estrogen Binding

Introduction

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