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Some of the materials available below are in Flash format. They require that the Flash plugin be installed on your browser. All the computers on campus should have this plugin installed on them. These materials can be both viewed on screen and printed.
- Lecture 0: A Physical Description of Nature
- Lecture 1: Transport Processes - Sedimentation
- Lecture 2: Calculus Review
- Lecture 3: Thermodynamics I - Heat, Work and Energy
- Lecture 4: Thermodynamics II - Entropy and Free Energy
- Lecture 5: Bioenergetics and Molecular Interactions
- Lecture 6: Proteins - Structure and Function
- Lecture 7: Structure Determination
Lecture 0: A Physical Description of Nature [TOC]
- Reading Assignment: Atkins, P and de Paula, J. (2006) Physical Chemistry for the Life Sciences; Fundamentals [flashpaper]
- Problem assignment: Problem Set 1 [flashpaper]
Lecture 1: Transport Processes - Sedimentation and Diffusion [TOC]
- Reading Assignment: van Holde, Johnson & Ho (1998) Principles of Physical Biochemistry; Chapter 5 [flashpaper]
- Problem assignment: Problem Set 2 [flashpaper]
- Theodor Svedberg (1884-1971) Nobel Prize in Chemistry, 1926
- Wilhelm Ostwald (1853-1932) Nobel Prize in Chemistry, 1909
Lecture 2: Calculus Review [TOC]
- Online Tutorials, Waner and Costenoble [html]
- Problem assignment: Problem Set 3 [flashpaper]
Lecture 3: Thermodynamics I - Heat, Work and Energy [TOC]
- Reading Assignment: Hammes, G; Thermodynamics and Kinetics for the Biological Sciences; Chapter 1 - Heat, Work and Energy [flashpaper]
- Reading Assignment: Atkins, P and de Paula, J.; Physical Chemistry for the Life Sciences; Chapter 1-Biochemical Thermodynamics:The First Law [pdf]
- Problem Set: Problem Set 4 [flashpaper]
- Problem Set: Problem Set 5 [flashpaper]
- Theremodynamic Data Sheets [pdf]
- Overheads: C406-Thermo-I [quicktime and flashpaper]
Lecture 4: Thermodynamics II - Entropy and Free Energy [TOC]
- Reading Assignment: Hammes, G; Thermodynamics and Kinetics for the Biological Sciences; Chapter 2 - Entropy and Free Energy [flashpaper]
- Reading Assignment: Atkins, P and de Paula, J.; Physical Chemistry for the Life Sciences; Chapter 2 - The Second Law [pdf]
- Reading Assignment: Atkins, P and de Paula, J.; Physical Chemistry for the Life Sciences; Chapter 4 - Chemical Equlibrium [pdf]
- Overheads: C406-Thermo-II [quicktime and flashpaper]
- Problem Set: Problem Set 6 [flashpaper]
Lecture 5: Bioenergetics and Molecular Interactions [TOC]
Bioenergetics
- Reading Assignment: Nelson, D & Cox, M: Lehninger's Biochemistry, 4thEdition [pdf]
- Overheads: C406-Bioenergetics [quicktime and flashpaper]
Interactions
- Reading Assignment: Atkins, P; The Elements of Physical Chemistry [pdf]
- Overheads: C406-Interactions [quicktime and flashpaper]
Lecture 6: Proteins - Structure and Function [TOC]
Lecture 7: Structure Determination [TOC]
X-ray Crystallography
- Lecture Notes: [pdf]
- Lecture Overheads [quicktime and pdf]
- Reading Assignment: Gale Rhodes; Crystallography Made Crystal Clear, 2ndEd.; Chapters 1 - Model and Molecule & Chapter 2 - An Overview of Protein Crystallography [pdf]
- Companion Web Site for Rhodes' Crystallography Made Crystal Clear [html]
- Kevin Cowtan's Book of Fortran [html]
- Kevin Cowtan's Interactive Structure Factor Applet [html]
- Bernhard Rupp's Crystallography 101 site [html]
