Pyruvate decarboxylase (E1), along with dihydrolipoyl transacetylase (E2) and dihydrolipoyl dehydrogenase (E3), plays an important role in the production of energy for the cell.  Together, these three components make up the pyruvate dehydrogenase complex (PDC)--an enzyme complex that converts the product of glycolysis, pyruvate, to acetyl coenzyme A, which serves as a starting point for the Citric Acid or TCA cycle.  However, this page only covers the first component--pyruvate decarboxylase.  If you need more information on the other components of PDC, go ahead and check out the other pages available to you.

• Function and Reaction Mechanism
• Structure
• Important Features
• References

    This web page project has been an adventure to say the least, but one worthwhile.  I hope you enjoy learning about the importance of protein interactions and their importance to our everyday living. 

Created By:John Hoberg/Chem 406 Student/University of Wisconsin-Eau Claire