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Chemistry 454-Biochemistry II
Homework
Problems 1-Metabolic Flux-the REAL meaning of
enzyme kinetics(Numerical
Simulation)-DUE 1/31 at the beginning of class. YOU CAN WORK IN GROUPS
OF TWO OR THREE BUT NO MORE.
In class I will hand out "Experiment" 5.3, Kinetic Analysis of Sequential Reactions.
This is a numerical model of non-enzyme kinetic behavior (but similar
in many ways to metabolism) that will help you become accustomed to
Excel Spreadsheet models. Answer
questions 1-7 concisely with tables and plots if requested. I
am giving you the first model below.Experiment 5.3-First Spreadsheet
Below is a spreadsheet and description of Problem 5.4 which explores the consequnces of having enzyme catalysts (with Km, Vmax, etc). Your assignment is to do Questions 1-3 and Problems 1-3 and 5 in Experiment 5.4. Be sure to show how you came to your conclusions, include any plots and answer questions as fully as you can.
Experiment 5.4-Problems/Introduction